{"product_id":"goodnight","title":"GoodNight","description":"\u003cp\u003eGoodNight - \u003cspan\u003eHerbal Support for Restful Sleep\u003c\/span\u003e\u003csup\u003e◆\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e60 Capsules - 30 Servings\u003c\/sup\u003e\u003c\/p\u003e\n\u003cdiv class=\"product info detailed collateral-container\"\u003e\n\u003cdiv class=\"product data items style1 stacked-tabs mage-tabs-disabled\" role=\"tablist\"\u003e\n\u003cdiv class=\"data item content\" id=\"description\" data-role=\"content\" aria-labelledby=\"tab-label-description\" role=\"tabpanel\" aria-hidden=\"false\"\u003e\n\u003cdiv class=\"product attribute description\"\u003e\n\u003cdiv class=\"value\"\u003e\n\u003cp\u003eGoodNight is an herbal formulation to promote restful sleep.\u003csup\u003e◆\u003c\/sup\u003e A comprehensive blend of sleep supporting vitamins, herbs, and amino acids help promote decreased sleep onset time and healthy sleep quality.\u003csup\u003e◆\u003c\/sup\u003e Insomnia affects nearly one-third of the adult US population causing significant economic, behavioral, and social issues. Herbal remedies may support restful sleep with fewer side effects than conventional approaches.\u003csup\u003e◆\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003eThe ingredients in GoodNight are dosed in a manner that is congruous with what research suggests to be effective and safe, particularly for promoting restful sleep.\u003csup\u003e◆\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003eClinical evidence and research cited herein shows that the ingredients in GoodNight may:\u003cbr\u003e\u003cbr\u003e● Support decreased sleep onset time\u003csup\u003e◆\u003c\/sup\u003e \u003cbr\u003e● Promote healthy sleep quality\u003csup\u003e◆\u003c\/sup\u003e\u003cbr\u003e● Support mood\u003csup\u003e◆\u003c\/sup\u003e\u003cbr\u003e● Support free radical scavenging activity\u003csup\u003e◆\u003c\/sup\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"detaillist-block\"\u003e\n\u003cdiv class=\"detaillist-blck recommendations\"\u003e\n\u003cdiv class=\"label\"\u003eRecommendations :\u003c\/div\u003e\n\u003cdiv class=\"data\"\u003eTake one or two capsules one hour before bedtime or as directed by your healthcare practitioner.\u003c\/div\u003e\n\u003cdiv class=\"data\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003eHow GoodNight Works\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eClinical studies show that dietary intake of vitamin B6 correlates with sleep quality.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 3, 4 Vitamin B6 must be obtained through diet and plays a critical role in the synthesis of neurotransmitters involved in the central nervous system and sleep patterns.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 4\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eFurthermore, dietary intake of foods containing tryptophan also reveals their ability to support healthy sleep quality.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 3 Tryptophan is an essential amino acid and a precursor of serotonin, which also plays a critical role in supporting sleep onset due to its direct effect on GABAergic neurons.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 5, 6 Serotonin is involved in many central nervous system functions, including sleep.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 6\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eMelatonin, a lipid-soluble indolamine, is produced from serotonin in the pineal gland.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 6, 7 It plays a role in sleep quality by signaling and reporting to cells about environmental factors leading to sleep, such as the onset of nighttime.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 6, 7 Melatonin also is a potent free radical scavenger.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 6\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eL-theanine is a neurologically active amino acid that stimulates alpha brain waves, creating a sense of deep relaxation.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 8 L-theanine also plays a role in the formation of GABA, resulting in its ability to induce relaxation.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 8\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eThe herbal ingredients include hops, lemon balm, and valerian root, which are known to possess relaxation effects due to their role as GABA receptors and support the central nervous system.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 1, 6,  9 The plant flavonoid compounds bind to recep tors to promote deeper sleep.\u003cspan style=\"font-family: Symbol; mso-ascii-font-family: Aptos; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Aptos; mso-hansi-theme-font: minor-latin; mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003e\u003cspan style=\"mso-char-type: symbol; mso-symbol-font-family: Symbol;\"\u003et\u003c\/span\u003e\u003c\/span\u003e 2\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003eReferences: \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e1. ** Bent, S., Padula, A., Moore, D., Patterson, M., \u0026amp; Mehling, W. (2006). Valerian for sleep: A systematic review and meta-analysis. The American Journal of Medicine, 119(12), 1005-1012. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e2. Gyllenhaal, C., Merritt, S. L., Peterson, S. D., Block, K. I., \u0026amp; Gochenour, T. (2000). Efficacy and safety of herbal stimulants and sedatives in sleep disorders. Sleep Medicine Reviews, 4(3), 229-251. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e3. Peuhkuri, K., Sihvola, N., \u0026amp; Korpela, R. (2012). Diet promotes sleep duration and quality. Nutrition Research, 32(5), 309-319. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e4. Fernstrand, P. L., \u0026amp; Garssen, J. (2015). The effect of dietary intake of vitamin B6 on sleep quality and insomnia. European Neuropsychopharmacology, 25(S2), 654. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e5. Lieberman, H. R., Agarwal, S., \u0026amp; Fulgoni, V. L. (2016). Tryptophan intake in the US adult population is not related to liver or kidney function but is associated with depression and sleep outcomes. The Journal of Nutrition, 146(12), 2609S-2615S. 6. Bravo, R., Franco, L., Rodriguez, A. B., Ugartemendia, L., Barriga, C., \u0026amp; Cubero, J. (2018). Tryptophan and hops: Chrononutrition tools to improve sleep\/wake circadian rythms. Annals of Clinical Nutrition, 1-7. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e7. Heminger, B., \u0026amp; Sheridan, D. (2018). Could melatonin be the cure for sleepless nights? Nursing, 48(1), 69. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e8. Mason, R. (2001). 200 mg of zen. Alternative and Complementary Therapies, 91-95. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e9. Taavoni, S., Nazem Ekbatani, N., \u0026amp; Haghani, H. (2013). Valerian\/lemon balm use for sleep disorders during menopause. ComplementaryTherapies in Clinical Practice, 19(4), 193-196.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; line-height: normal;\"\u003e\u003cspan style=\"font-size: 9.0pt;\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"margin-bottom: 0in; mso-add-space: auto; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-family: Symbol; mso-fareast-font-family: Symbol; mso-bidi-font-family: Symbol;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e·\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e         * \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e","brand":"Marcus Institute of Integrative Health","offers":[{"title":"Default Title","offer_id":68265915089200,"sku":null,"price":34.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1115\/4692\/files\/GoodNight01.webp?v=1793902997","url":"https:\/\/marcusstore.jeffersonhealth.org\/products\/goodnight","provider":"Marcus Institute of Integrative Health","version":"1.0","type":"link"}