SPM Advanced is a revolutionary nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil. SPMs play a key role in the resolution (i.e., completion) of an immune response, according to extensive preclinical research.

Broad Spectrum Flora provides multidimensional support for both the upper and lower GI tract for digestive and immune health.* This concentrated formula supplies a proprietary blend of 7 beneficial probiotic strains including L. acidophilus NCFM®, B. lactis Bi-07, B. lactis Bl-04, L. salivarius Ls-33, and L. plantarum Lp-115.

While vitamin D has long been known to assist calcium absorption, it is vitamin K, through its carboxylation of osteocalcin, which guides this calcium to bones and prevents their absorption into organs, joint spaces and arteries. Vitamin K occurs in 3 main forms: K1 (phylloquinone), derived from foods such as green leafy vegetables, K2 (menaquinone) which originates from bacteria; a third form, K3 (menadione), is a synthetic analogue. Numerous studies have shown that vitamin K2 is the more bioavailable form of the nutrient, and more powerfully influences bone building than K1. There are two forms of vitamin K2 commonly used in supplements: MK-4 and MK-7. The MK-7 form has been shown to have six times the activity of MK-4 in the blood. MK-7 has also been found to remain in the blood approximately nine times as long as the MK-4 (8 hours versus 72 hours), making it the optimal form of K2 for health. A growing body of research shows that when it comes to bone health, ensuring optimal intake of vitamin K is a critical piece of the puzzle. New research is focusing on the synergistic relationship between vitamin K (specifically, vitamin K2) and vitamin D3, especially in terms of bone strength and cardiovascular health. Through its activation of the protein osteocalcin, vitamin K helps to bind newly absorbed calcium to the mineral matrix in bone. In addition, vitamin K has been found to help maintain bone mineral density by decreasing the activity of osteoclasts, a cell that breaks down the bone matrix. Thus, vitamin K and vitamin D not only share similar qualities, but also act synergistically with one another within the body. The Vitamin K2 with D3 formula includes 45 mcg of vitamin K2 delivered as MK-7 and 5,000 IU of vitamin D3 per capsule, for optimal absorption by the body.

Homocysteine Metabolism Support™ is a comprehensive formula that features calcium L-5-methyltetrahydrofolate— a body-ready, nature identical folate—along with N-Acetyl-L-Cysteine, vitamins B6 and methylated B12, and betaine HCl. Together, these nutrients support methylation, which promotes healthy homocysteine metabolism.*

UltraGI Replenish® is a medical food formulated to provide specialized macro-and micronutrient support for patients challenged by compromised gut function with digestive disorders including malabsorption. It is designed to complement an eating plan that excludes common food allergens and supports healthy gut function.

TRF 150™ and TRF 350™ provide nutritional support for healthy joint function. These products feature Cyplexinol® PRO, a bone derived protein/collagen complex containing Bone Morphogenetic Proteins (BMPs) and key growth factors naturally contained in bone. This ingredient helps to support the pathways involved in normal bone remodeling, and in the normal repair and regeneration of cartilage, thereby supporting good bone health and joint integrity.**

IB Flora is a clinically tested blend of “friendly” bacteria in a dairy free base. This advanced formula is designed to help address gastrointestinal symptoms such as abdominal discomfort, bloating, cramping, and occasional urgency. Backed by the Metagenics ID Guarantee for purity, clinical reliability, and predicted safety via scientific identification of strains with established health benefits.*

D3 5000™ features 5,000 IU of vitamin D3 in easy-to-swallow softgels. This bioavailable form of vitamin D is solubilized in oil to support absorption in the intestinal tract.

This 200mg dose of highly bioavailable ubiquinone CoQ10 features DFH's proprietary Evail technology. CoQ10 is a natural process that improves the absorption and delivery of nutrients that are difficult to absorb.* CoQ10 utilizes a proprietary blend of vitamin E, sunflower lecithin. Unlike other commonly available emulsified or micellized formulas, this product achieves enhanced absorption without potentially harmful agents such as polysorbate 80 and black pepper extracts.* Superior bioavailability has been demonstrated in an in-house human clinical trial, showing this material to be up to 390% more bioavailable than DFH's previous, superior absorption, CoQ10 formulation. * This product is Non-GMO and Gluten-Free.