With its potent antioxidant properties, research has shown alpha lipoic acid (ALA) strongly supports the neurovascular system, as well as overall circulatory and blood vessel health. As a short chain fatty acid, ALA can both be absorbed by fatty tissues and maintain its solubility in water, allowing it to be easily excreted from the body when not needed. In addition, orally supplemented ALA readily crosses the blood brain barrier after absorption in the small intestine; thereafter, it undergoes distribution via systemic circulation. Once inside the tissues, ALA can exert antioxidant benefits inside and outside the cells. ALA serves as a sulfur donor, which allows it to support detoxification pathways. Studies have shown that ALA also modulates the expression of genes, allowing it to support blood sugar balance and cardiometabolic health. This formulation of Lipoic Acid includes 300 mg of ALA, as well as 300 mcg of biotin to protect against the loss of biotin as a result of the competition between the two nutrients.

Calcium is required for strong bones, heart health, muscle function, nerve transmission, intracellular signaling and hormonal secretion. It is less than 1% of total body calcium that supports these critical metabolic functions. The body uses bone tissue as a reservoir for calcium, as well as a source of calcium, to maintain constant concentrations of calcium in blood, muscle and intercellular fluids. The remaining 99% of the calcium supply in the body is stored in the bones and teeth, serving as a mineral reserve and structural support for the body. Activated Calcium provides three unique forms of highly-absorbed calcium to ensure maximum absorption of this important macromineral. While most calcium supplements use only a single source of calcium, which can easily overwhelm a single pathway of absorption and limit uptake, Activated Calcium takes advantage of three unique pathways of absorption by providing calcium in the hydroxyapatite, di-calcium malate, and glycinate forms. In addition, Activated Calcium includes vitamin D and phosphorus, both critical nutrients for bone mineralization and remodeling.

While vitamin D has long been known to assist calcium absorption, it is vitamin K, through its carboxylation of osteocalcin, which guides this calcium to bones and prevents their absorption into organs, joint spaces and arteries. Vitamin K occurs in 3 main forms: K1 (phylloquinone), derived from foods such as green leafy vegetables, K2 (menaquinone) which originates from bacteria; a third form, K3 (menadione), is a synthetic analogue. Numerous studies have shown that vitamin K2 is the more bioavailable form of the nutrient, and more powerfully influences bone building than K1. There are two forms of vitamin K2 commonly used in supplements: MK-4 and MK-7. The MK-7 form has been shown to have six times the activity of MK-4 in the blood. MK-7 has also been found to remain in the blood approximately nine times as long as the MK-4 (8 hours versus 72 hours), making it the optimal form of K2 for health. A growing body of research shows that when it comes to bone health, ensuring optimal intake of vitamin K is a critical piece of the puzzle. New research is focusing on the synergistic relationship between vitamin K (specifically, vitamin K2) and vitamin D3, especially in terms of bone strength and cardiovascular health. Through its activation of the protein osteocalcin, vitamin K helps to bind newly absorbed calcium to the mineral matrix in bone. In addition, vitamin K has been found to help maintain bone mineral density by decreasing the activity of osteoclasts, a cell that breaks down the bone matrix. Thus, vitamin K and vitamin D not only share similar qualities, but also act synergistically with one another within the body. The Vitamin K2 with D3 formula includes 45 mcg of vitamin K2 delivered as MK-7 and 5,000 IU of vitamin D3 per capsule, for optimal absorption by the body.

Inflammation is a natural part of the body’s immune response, a cascade triggered to protect the body and maintain normal tissue repair. This physiological response is part of the innate immune or non-specific immune system, a first line of defense comprising the cells and mechanisms that defend against unwanted organisms in a non-specific manner. The inflammatory cascade is mediated by eicosanoids, which have been shown to balance inflammation and immunemodulating cytokines. Inflamma-Shield provides a blend of nutrients which support a healthy inflammatory cycle by balancing eicosanoid and cytokine metabolism and inhibiting the activities and synthesis of a wide variety of compounds implicated in pain and inflammation. Traumeric is formulated specifically to support healthy inflammatory balance and musculoskeletal health. Inflamma-Shield includes key ingredient turmeric, standardized to include 95% of curcumin. Inflamma-Shield also includes the pineapple enzyme bromelain, as well as flavonoids quercetin and rutin for full-spectrum, high-intensity support to maintain a balanced cycle of inflammation.

Magnesium is an abundant mineral in the body and is found naturally in many foods, like green leafy vegetables. It is also found in over-the-counter medications, such as laxatives. The average American intake of magnesium, according to the National Health and Nutrition Examination Survey (NHANES Study) is critically low: Many Americans fail to consume the estimated average requirement (EAR) established by the Institute of Medicine. In addition, more than 57% of the population does not meet the United States Department of Agriculture requirements for magnesium in the diet. Intracellular magnesium levels are decreased by excessive intake of alcohol, salt, coffee, phosphoric acid found in sodas, diets high in calcium and high stress levels. Because of widespread nature of magnesium deficiencies, adequate daily intake of magnesium is critical for proper hydration, stress response, muscle relaxation, promoting healthy blood pressure levels, optimal bone mineral density, and blood sugar regulation. Reacted Magnesium provides three unique forms of highly-absorbed magnesium to ensure maximum absorption of this important macromineral. Most magnesium supplements use only a single source of magnesium, which can easily overwhelm a single pathway of absorption and limit uptake. Reacted Magnesium takes advantage of three unique pathways of absorption by providing magnesium as di-magnesium malate, magnesium citrate and magnesium glycinate for enhanced absorption, improved utilization and gastrointestinal (GI) comfort. Some individuals, who take other forms of magnesium supplements, often experience GI side effects, including gas, bloating, diarrhea, constipation or a combination of these symptoms. The forms of magnesium used in Reacted Magnesium preserve GI comfort while maximizing absorption and restoring magnesium levels in the body.

N-acetyl cysteine (NAC) is an amino acid that boosts antioxidant function and is a source of the conditionally essential amino acid L-cysteine. It has also been found to raise glutathione levels. Glutathione is an important antioxidant used in many different metabolic processes within the body. Maintaining adequate levels is important to maintaining the health of the respiratory, hepatic, and immune systems. It is also important in supporting antioxidant protection of lipids and proteins and supporting the normal response to inflammation. NAC is commonly used as an agent to help clear sinus and airway congestion caused by mucus overproduction. It also supports antioxidant and cellular detoxification pathways in the body. Each capsule of the N-Acetyl Cysteine formulation includes 500 mg of this versatile amino acid.